BPES_FOXL2

Gene
FOXL2
Disease
BPES
Inheritance
AD, AR
Classification
Definitive
Total Score
14.5
Publications Reviewed
6
Publication Span
7.08 years
Last Updated
06/04/2025
Curator(s)
Laurel Hiatt

Genetic evidence

Total: 9

Singular EvidenceProbandsPMID:114682772.55, probands and sporadic
Singular EvidenceProbandsPMID:272830353.55 probands, some with multiple generations, etc
Collective EvidenceComputationalPMID:338759391Highly conserved
Collective EvidenceSegregationPMID:338759392lod score ~3.9 i think, panel/targeted sequencing
4 rows

Experimental evidence

Total: 5.5

ModelsCell culturePMID:155912791
Functional AlterationNon-patient cellsPMID:183723160.5
ModelsNon-Human Model OrganismPMID:222488224Review describes multiple animal models, cell models and protein alteration. Here scored based on animal models.
3 rows

Note: Maximum score caps apply at evidence type, category, and supercategory levels, so section totals may be lower than the raw sum of row scores.