NIID_NOTCH2NLC

Gene
NOTCH2NLC
Disease
NIID
Inheritance
AD
Classification
Definitive
Total Score
18
Publications Reviewed
5
Publication Span
5 years
Last Updated
8/14/25
Curator(s)
Macayla Weiner, Laurel Hiatt

Note: Maximum score caps apply at evidence type, category, and supercategory levels, so section totals may be lower than the raw sum of row scores.

Genetic evidence

Total: 12

Singular EvidenceProbandsPMID:370909346
Collective EvidenceSegregationPMID:311781261.5
StatisticsCase-control dataPMID:36570826 PMID:36086903 PMID:35857137 PMID:346751066
3 rows

Experimental evidence

Total: 6

FunctionBiochemical functionPMID:313323800.5
FunctionProtein interactionPMID:313323800.5
FunctionRegulatory ImpactPMID:313323801Expression, epigenetic
Functional AlterationPatient cellsPMID:390559601
Functional AlterationNon-patient cellsPMID:390559600.5
ModelsNon-human model organismPMID:390559604fly and mouse
6 rows