SCA4_ZFHX3
- Gene
- ZFHX3
- Disease
- SCA4
- Inheritance
- AD
- Classification
- Definitive
- Total Score
- 13.5
- Publications Reviewed
- 5
- Publication Span
- 21 years
- Last Updated
- 8/18/25
- Curator(s)
- Macayla Weiner, Laurel Hiatt
Note: Maximum score caps apply at evidence type, category, and supercategory levels, so section totals may be lower than the raw sum of row scores.
Genetic evidence
Total: 9.5
| Singular Evidence | Probands | PMID:38035881 | 6 | 5 probands | ||
| Collective Evidence | Allele | PMID:39095619 | 2 | |||
| Collective Evidence | Segregation | PMID:12796826 | 1.5 |
3 rows
Experimental evidence
Total: 4
| Function | Protein interaction | PMID:38684900 | 0.5 | |||
| Function | Regulatory Impact | PMID:38197134 PMID:38684900 PMID:39635987 PMID:40459184 | 1.5 | expression x2, methylation x2 | ||
| Functional Alteration | Patient cells | PMID:38684900 | 1 | |||
| Models | Cell culture | PMID:38684900 | 1 |
4 rows